1770
The Governor of Bombay William Hornby shifts his official residence to Parel, making it the seat of power. The government house was supposed to have been built on the site of an old temple of Parli Vaijnath, which gave the name Parel to the adjoining village.

1877
Parel Railway Station is opened. Many of the cotton mills were in this area until the beginning of the 21st century when most of these mills were shut down.

2016
The government house exists today as Haffkine Institute after the building was converted into a lab during the bubonic plague epidemic in 1896.